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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736260
Species: Mus musculus
RGD Object: Gene
Symbol: Eif2ak3
Name: eukaryotic translation initiation factor 2 alpha kinase 3
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eif2ak3affects expressionEXP 6480464CTDValproic Acid affects the expression of EIF2AK3 mRNAPMID:17963808
Eif2ak3increases expressionEXP 6480464CTDValproic Acid results in increased expression of EIF2AK3 mRNAPMID:19136453 PMID:21427059
Eif2ak3increases expressionISOEIF2AK3 (Homo sapiens)6480464CTDValproic Acid results in increased expression of EIF2AK3 mRNAPMID:26272509 PMID:28001369
Eif2ak3multiple interactionsISOEIF2AK3 (Homo sapiens)6480464CTD[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EIF2AK3 mRNAPMID:27188386
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