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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735621
Species: Homo sapiens
RGD Object: Gene
Symbol: CXCL2
Name: C-X-C motif chemokine ligand 2
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CXCL2decreases expressionEXP 6480464CTDValproic Acid results in decreased expression of CXCL2 mRNAPMID:29154799
CXCL2decreases methylationEXP 6480464CTDValproic Acid results in decreased methylation of CXCL2 genePMID:29154799
CXCL2increases expressionEXP 6480464CTDValproic Acid results in increased expression of CXCL2 mRNAPMID:24935251 PMID:28001369
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