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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731575
Species: Homo sapiens
RGD Object: Gene
Symbol: CALR
Name: calreticulin
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CALRdecreases expressionEXP 6480464CTDValproic Acid results in decreased expression of CALR mRNAPMID:32623605
CALRincreases expressionEXP 6480464CTDValproic Acid results in increased expression of CALR mRNAPMID:23179753
CALRmultiple interactionsEXP 6480464CTDCEBPA protein affects the reaction [Valproic Acid results in decreased expression of CALR mRNA]PMID:32623605
CALRincreases expressionISOCalr (Mus musculus)6480464CTDValproic Acid results in increased expression of CALR mRNAPMID:21427059
CALRincreases expressionISOCalr (Rattus norvegicus)6480464CTDValproic Acid results in increased expression of CALR proteinPMID:16236328
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