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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730878
Species: Homo sapiens
RGD Object: Gene
Symbol: NPPA
Name: natriuretic peptide A
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NPPAincreases methylationEXP 6480464CTDValproic Acid results in increased methylation of NPPA genePMID:29154799
NPPAincreases expressionISONppa (Rattus norvegicus)6480464CTDValproic Acid results in increased expression of NPPA mRNAPMID:29427782
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