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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708484
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc35e4
Name: solute carrier family 35, member E4
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc35e4affects expressionISORGD:16029596480464CTDValproic Acid affects the expression of SLC35E4 mRNA

PMID:25979313
Slc35e4increases expressionISORGD:16029596480464CTDValproic Acid results in increased expression of SLC35E4 mRNA

PMID:23179753, PMID:29154799
Slc35e4increases expressionISORGD:7340956480464CTDValproic Acid results in increased expression of SLC35E4 mRNA

PMID:21427059
Slc35e4increases methylationISORGD:16029596480464CTDValproic Acid results in increased methylation of SLC35E4 gene

PMID:29154799
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.