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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708356
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ppp2r2d
Name: protein phosphatase 2, regulatory subunit B, delta
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppp2r2daffects expressionISOPpp2r2d (Mus musculus)6480464CTDValproic Acid affects the expression of PPP2R2D mRNAPMID:17292431
Ppp2r2ddecreases expressionISOPpp2r2d (Mus musculus)6480464CTDValproic Acid results in decreased expression of PPP2R2D mRNAPMID:17963808 PMID:21427059
Ppp2r2dincreases expressionISOPPP2R2D (Homo sapiens)6480464CTDValproic Acid results in increased expression of PPP2R2D mRNAPMID:19101580
Ppp2r2dincreases methylationISOPPP2R2D (Homo sapiens)6480464CTDValproic Acid results in increased methylation of PPP2R2D genePMID:29154799
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