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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628651
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gm2a
Name: ganglioside GM2 activator
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gm2aaffects expressionISOGM2A (Homo sapiens)6480464CTDValproic Acid affects the expression of GM2A mRNAPMID:25979313
Gm2aincreases expressionISOGM2A (Homo sapiens)6480464CTDValproic Acid results in increased expression of GM2A mRNAPMID:19101580 PMID:23179753 PMID:23527032 PMID:24383497 PMID:26272509 PMID:28001369 PMID:29154799
Gm2amultiple interactionsISOGM2A (Homo sapiens)6480464CTD[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GM2A mRNAPMID:27188386
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