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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620585
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Elovl6
Name: ELOVL fatty acid elongase 6
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Elovl6affects expressionISOElovl6 (Mus musculus)6480464CTDValproic Acid affects the expression of ELOVL6 mRNAPMID:17963808
Elovl6affects expressionISOELOVL6 (Homo sapiens)6480464CTDValproic Acid affects the expression of ELOVL6 mRNAPMID:25979313
Elovl6decreases expressionISOELOVL6 (Homo sapiens)6480464CTDValproic Acid results in decreased expression of ELOVL6 mRNAPMID:23179753 PMID:27188386 PMID:29154799
Elovl6increases expressionISOELOVL6 (Homo sapiens)6480464CTDValproic Acid results in increased expression of ELOVL6 mRNA; Valproic Acid results in increased expression of ELOVL6 proteinPMID:24935251 PMID:30003287
Elovl6multiple interactionsISOELOVL6 (Homo sapiens)6480464CTD[Hydralazine co-treated with Valproic Acid] results in increased expression of ELOVL6 mRNA; NR1H3 protein affects the reaction [Valproic Acid results in increased expression of ELOVL6 mRNA]PMID:17183730 PMID:30003287
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