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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61912
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc6a6
Name: solute carrier family 6 member 6
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc6a6affects splicingEXP 6480464CTDValproic Acid affects the splicing of SLC6A6 mRNAPMID:29427782
Slc6a6increases expressionISOSLC6A6 (Homo sapiens)6480464CTDValproic Acid results in increased expression of SLC6A6 mRNAPMID:24383497 PMID:24935251
Slc6a6increases methylationISOSLC6A6 (Homo sapiens)6480464CTDValproic Acid results in increased methylation of SLC6A6 genePMID:29154799
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