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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3679
Species: Rattus norvegicus
RGD Object: Gene
Symbol: St8sia1
Name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
St8sia1affects expressionISOST8SIA1 (Homo sapiens)6480464CTDValproic Acid affects the expression of ST8SIA1 mRNAPMID:25979313
St8sia1decreases expressionISOST8SIA1 (Homo sapiens)6480464CTDValproic Acid results in decreased expression of ST8SIA1 mRNAPMID:23179753
St8sia1increases expressionISOST8SIA1 (Homo sapiens)6480464CTDValproic Acid results in increased expression of ST8SIA1 mRNAPMID:26272509
St8sia1multiple interactionsISOST8SIA1 (Homo sapiens)6480464CTD[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ST8SIA1 mRNAPMID:27188386
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