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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3140
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Myh9
Name: myosin, heavy chain 9
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionISORGD:7324016480464CTDValproic Acid affects the expression of MYH9 mRNA

PMID:25979313
decreases methylationISORGD:7324016480464CTDValproic Acid results in decreased methylation of MYH9 gene

PMID:29154799
increases expressionISORGD:7324016480464CTDValproic Acid results in increased expression of MYH9 mRNA

PMID:23179753, PMID:26238599
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.