GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Egf | affects expression | ISO | EGF (Homo sapiens) | 6480464 | CTD | Valproic Acid affects the expression of EGF mRNA | PMID:25979313 | Egf | decreases expression | ISO | EGF (Homo sapiens) | 6480464 | CTD | Valproic Acid results in decreased expression of EGF mRNA | PMID:23179753 PMID:24383497 PMID:26272509 | Egf | increases expression | ISO | EGF (Homo sapiens) | 6480464 | CTD | Valproic Acid results in increased expression of EGF mRNA | PMID:23179753 PMID:27188386 | Egf | multiple interactions | ISO | EGF (Homo sapiens) | 6480464 | CTD | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of EGF mRNA; U 0126 inhibits the reaction [Valproic Acid promotes the reaction [EGF protein results in increased activity of ELK1 protein]]; Valproic Acid promotes the reaction [EGF protein results in increased activity of ELK1 protein] | PMID:15103026 PMID:27188386 | |
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