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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2079
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akap11
Name: A-kinase anchoring protein 11
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akap11affects splicingEXP 6480464CTDValproic Acid affects the splicing of AKAP11 mRNA

PMID:29427782
Akap11decreases expressionISORGD:7362766480464CTDValproic Acid results in decreased expression of AKAP11 mRNA

PMID:23527032
Akap11decreases methylationISORGD:7362766480464CTDValproic Acid results in decreased methylation of AKAP11 gene

PMID:29154799
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.