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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1619031
Species: Mus musculus
RGD Object: Gene
Symbol: Tet3
Name: tet methylcytosine dioxygenase 3
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tet3affects expressionISOTET3 (Homo sapiens)6480464CTDValproic Acid affects the expression of TET3 mRNAPMID:25979313
Tet3affects splicingISOTet3 (Rattus norvegicus)6480464CTDValproic Acid affects the splicing of TET3 mRNAPMID:29427782
Tet3increases methylationISOTET3 (Homo sapiens)6480464CTDValproic Acid results in increased methylation of TET3 genePMID:29154799
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