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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1615726
Species: Mus musculus
RGD Object: Gene
Symbol: Nckap5
Name: NCK-associated protein 5
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nckap5decreases expressionISORGD:16250926480464CTDValproic Acid results in decreased expression of NCKAP5 mRNA

PMID:23179753, PMID:25192806
Nckap5decreases methylationISORGD:16250926480464CTDValproic Acid results in decreased methylation of NCKAP5 gene

PMID:29154799
Nckap5increases expressionISORGD:16250926480464CTDValproic Acid results in increased expression of NCKAP5 mRNA

PMID:24383497, PMID:29154799
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.