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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1607007
Species: Homo sapiens
RGD Object: Gene
Symbol: RTN4R
Name: reticulon 4 receptor
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
RTN4Rincreases methylationEXP 6480464CTDValproic Acid results in increased methylation of RTN4R genePMID:29154799
RTN4Rdecreases expressionISORtn4r (Mus musculus)6480464CTDValproic Acid results in decreased expression of RTN4R mRNAPMID:29261810
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