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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1560653
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fam131b
Name: family with sequence similarity 131, member B
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fam131baffects expressionISOFAM131B (Homo sapiens)6480464CTDValproic Acid affects the expression of FAM131B mRNAPMID:25979313
Fam131bdecreases expressionISOFAM131B (Homo sapiens)6480464CTDValproic Acid results in decreased expression of FAM131B mRNAPMID:23179753 PMID:26272509 PMID:28001369
Fam131bincreases expressionISOFAM131B (Homo sapiens)6480464CTDValproic Acid results in increased expression of FAM131B mRNAPMID:19101580
Fam131bincreases methylationISOFAM131B (Homo sapiens)6480464CTDValproic Acid results in increased methylation of FAM131B genePMID:29154799
Fam131bmultiple interactionsISOFAM131B (Homo sapiens)6480464CTD[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FAM131B mRNAPMID:27188386
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