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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1560552
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Eefsec
Name: eukaryotic elongation factor, selenocysteine-tRNA-specific
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eefsecaffects expressionISOEefsec (Mus musculus)6480464CTDValproic Acid affects the expression of EEFSEC mRNAPMID:17292431
Eefsecaffects expressionISOEEFSEC (Homo sapiens)6480464CTDValproic Acid affects the expression of EEFSEC mRNAPMID:25979313
Eefsecdecreases methylationISOEEFSEC (Homo sapiens)6480464CTDValproic Acid results in decreased methylation of EEFSEC genePMID:29154799
Eefsecincreases expressionISOEEFSEC (Homo sapiens)6480464CTDValproic Acid results in increased expression of EEFSEC mRNAPMID:28001369
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