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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552910
Species: Mus musculus
RGD Object: Gene
Symbol: Pbx1
Name: pre B cell leukemia homeobox 1
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pbx1increases expressionEXP 6480464CTDValproic Acid results in increased expression of PBX1 mRNAPMID:22045034
Pbx1affects splicingISOPbx1 (Rattus norvegicus)6480464CTDValproic Acid affects the splicing of PBX1 mRNAPMID:29427782
Pbx1decreases expressionISOPBX1 (Homo sapiens)6480464CTDValproic Acid results in decreased expression of PBX1 mRNAPMID:23527032 PMID:24935251 PMID:28001369
Pbx1increases expressionISOPBX1 (Homo sapiens)6480464CTDValproic Acid results in increased expression of PBX1 mRNAPMID:23179753
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