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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551192
Species: Mus musculus
RGD Object: Gene
Symbol: Id2
Name: inhibitor of DNA binding 2
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Id2affects expressionEXP 6480464CTDValproic Acid affects the expression of ID2 mRNAPMID:17292431
Id2increases expressionEXP 6480464CTDValproic Acid results in increased expression of ID2 mRNAPMID:21427059
Id2affects expressionISOID2 (Homo sapiens)6480464CTDValproic Acid affects the expression of ID2 mRNAPMID:25979313
Id2decreases expressionISOID2 (Homo sapiens)6480464CTDValproic Acid results in decreased expression of ID2 mRNAPMID:29154799
Id2increases expressionISOID2 (Homo sapiens)6480464CTDValproic Acid results in increased expression of ID2 mRNAPMID:23179753 PMID:26272509
Id2multiple interactionsISOID2 (Homo sapiens)6480464CTD[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ID2 mRNAPMID:27188386
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