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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1354298
Species: Homo sapiens
RGD Object: Gene
Symbol: PDIA6
Name: protein disulfide isomerase family A member 6
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PDIA6affects expressionEXP 6480464CTDValproic Acid affects the expression of PDIA6 mRNAPMID:25979313
PDIA6increases expressionEXP 6480464CTDValproic Acid results in increased expression of PDIA6 mRNAPMID:23179753
PDIA6increases methylationEXP 6480464CTDValproic Acid results in increased methylation of PDIA6 genePMID:29154799
PDIA6decreases expressionISOPdia6 (Rattus norvegicus)6480464CTDValproic Acid results in decreased expression of PDIA6 mRNAPMID:21318169
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