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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1353919
Species: Homo sapiens
RGD Object: Gene
Symbol: CRY1
Name: cryptochrome circadian regulator 1
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CRY1affects expressionEXP 6480464CTDValproic Acid affects the expression of CRY1 mRNAPMID:25979313
CRY1decreases methylationEXP 6480464CTDValproic Acid results in decreased methylation of CRY1 genePMID:29154799
CRY1increases expressionEXP 6480464CTDValproic Acid results in increased expression of CRY1 mRNAPMID:22083351 PMID:29154799
CRY1increases expressionISOCry1 (Mus musculus)6480464CTDValproic Acid results in increased expression of CRY1 mRNAPMID:29229235
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