GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | NANOG | decreases expression | EXP | | 6480464 | CTD | Valproic Acid results in decreased expression of NANOG mRNA | PMID:23179753 PMID:27188386 PMID:29775723 | NANOG | increases expression | EXP | | 6480464 | CTD | Valproic Acid results in increased expression of NANOG mRNA | PMID:22723015 PMID:23179753 PMID:24383497 PMID:24935251 PMID:26272509 | NANOG | multiple interactions | EXP | | 6480464 | CTD | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NANOG mRNA; Valproic Acid inhibits the reaction [[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with LDN 193189] results in decreased expression of NANOG mRNA] | PMID:27188386 PMID:32949729 | |
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