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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1345096
Species: Homo sapiens
RGD Object: Gene
Symbol: PSME4
Name: proteasome activator subunit 4
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PSME4decreases expressionEXP 6480464CTDValproic Acid results in decreased expression of PSME4 mRNAPMID:23179753 PMID:27188386
PSME4increases expressionEXP 6480464CTDValproic Acid results in increased expression of PSME4 mRNAPMID:29154799
PSME4affects splicingISOPsme4 (Rattus norvegicus)6480464CTDValproic Acid affects the splicing of PSME4 mRNAPMID:29427782
PSME4increases expressionISOPsme4 (Rattus norvegicus)6480464CTDValproic Acid results in increased expression of PSME4 mRNAPMID:21318169
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