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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344840
Species: Homo sapiens
RGD Object: Gene
Symbol: ACOX1
Name: acyl-CoA oxidase 1
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ACOX1affects expressionEXP 6480464CTDValproic Acid affects the expression of ACOX1 mRNAPMID:25979313
ACOX1decreases expressionEXP 6480464CTDValproic Acid results in decreased expression of ACOX1 mRNAPMID:29501571
ACOX1increases expressionEXP 6480464CTDValproic Acid results in increased expression of ACOX1 mRNAPMID:23179753 PMID:28001369 PMID:33901630
ACOX1increases methylationEXP 6480464CTDValproic Acid results in increased methylation of ACOX1 genePMID:29501571
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