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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1323703
Species: Homo sapiens
RGD Object: Gene
Symbol: UQCRB
Name: ubiquinol-cytochrome c reductase binding protein
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
UQCRBaffects expressionEXP 6480464CTDValproic Acid affects the expression of UQCRB mRNAPMID:25979313
UQCRBdecreases methylationEXP 6480464CTDValproic Acid results in decreased methylation of UQCRB genePMID:29154799
UQCRBincreases expressionEXP 6480464CTDValproic Acid results in increased expression of UQCRB mRNAPMID:23179753 PMID:25192806 PMID:27188386 PMID:28001369
UQCRBmultiple interactionsEXP 6480464CTD[Hydralazine co-treated with Valproic Acid] results in increased expression of UQCRB mRNAPMID:17183730
UQCRBaffects expressionISOUqcrb (Mus musculus)6480464CTDValproic Acid affects the expression of UQCRB mRNAPMID:17292431
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