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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1320833
Species: Mus musculus
RGD Object: Gene
Symbol: Tnfrsf14
Name: tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfrsf14decreases expressionISOTnfrsf14 (Rattus norvegicus)6480464CTDValproic Acid results in decreased expression of TNFRSF14 mRNAPMID:35594946
Tnfrsf14increases methylationISOTNFRSF14 (Homo sapiens)6480464CTDValproic Acid results in increased methylation of TNFRSF14 genePMID:29154799
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