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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1313987
Species: Mus musculus
RGD Object: Gene
Symbol: Xpc
Name: xeroderma pigmentosum, complementation group C
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Xpcaffects expressionISOXPC (Homo sapiens)6480464CTDValproic Acid affects the expression of XPC mRNAPMID:25979313
Xpcincreases expressionISOXPC (Homo sapiens)6480464CTDValproic Acid results in increased expression of XPC mRNAPMID:21507255
Xpcmultiple interactionsISOXPC (Homo sapiens)6480464CTDValproic Acid promotes the reaction [CREB1 protein binds to XPC promoter]; Valproic Acid promotes the reaction [SP1 protein binds to XPC promoter]PMID:21507255
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