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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309076
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc35e2b
Name: solute carrier family 35, member E2B
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc35e2baffects expressionISOSlc35e2 (Mus musculus)6480464CTDValproic Acid affects the expression of SLC35E2 mRNAPMID:17292431
Slc35e2bdecreases expressionISOSLC35E2B (Homo sapiens)6480464CTDValproic Acid results in decreased expression of SLC35E2B mRNAPMID:23179753 PMID:26272509 PMID:28001369
Slc35e2bincreases methylationISOSLC35E2B (Homo sapiens)6480464CTDValproic Acid results in increased methylation of SLC35E2B genePMID:29154799
Slc35e2bmultiple interactionsISOSLC35E2B (Homo sapiens)6480464CTD[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC35E2B mRNAPMID:27188386
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