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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308692
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nfatc3
Name: nuclear factor of activated T-cells 3
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfatc3decreases methylationISONFATC3 (Homo sapiens)6480464CTDValproic Acid results in decreased methylation of NFATC3 genePMID:29154799
Nfatc3increases expressionISONFATC3 (Homo sapiens)6480464CTDValproic Acid results in increased expression of NFATC3 mRNAPMID:29501571
Nfatc3increases methylationISONFATC3 (Homo sapiens)6480464CTDValproic Acid results in increased methylation of NFATC3 genePMID:29501571
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