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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308318
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mrps5
Name: mitochondrial ribosomal protein S5
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mrps5decreases expressionISORGD:13180206480464CTDValproic Acid results in decreased expression of MRPS5 mRNA

PMID:23179753, PMID:27188386
Mrps5multiple interactionsISORGD:13180206480464CTD[Hydralazine co-treated with Valproic Acid] results in increased expression of MRPS5 mRNA

PMID:17183730
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.