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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307224
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rictor
Name: RPTOR independent companion of MTOR, complex 2
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rictoraffects splicingEXP 6480464CTDValproic Acid affects the splicing of RICTOR mRNAPMID:29427782
Rictordecreases expressionEXP 6480464CTDValproic Acid results in decreased expression of RICTOR mRNAPMID:29427782
Rictoraffects expressionISORICTOR (Homo sapiens)6480464CTDValproic Acid affects the expression of RICTOR mRNAPMID:25979313
Rictordecreases expressionISORICTOR (Homo sapiens)6480464CTDValproic Acid results in decreased expression of RICTOR mRNAPMID:23179753 PMID:25192806 PMID:27188386
Rictordecreases methylationISORICTOR (Homo sapiens)6480464CTDValproic Acid results in decreased methylation of RICTOR genePMID:29154799
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