Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305897
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mrrf
Name: mitochondrial ribosome recycling factor
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mrrfaffects expressionISOMrrf (Mus musculus)6480464CTDValproic Acid affects the expression of MRRF mRNAPMID:17963808
Mrrfdecreases methylationISOMRRF (Homo sapiens)6480464CTDValproic Acid results in decreased methylation of MRRF genePMID:29154799
Mrrfincreases expressionISOMRRF (Homo sapiens)6480464CTDValproic Acid results in increased expression of MRRF mRNAPMID:26272509
Mrrfmultiple interactionsISOMRRF (Homo sapiens)6480464CTD[Hydralazine co-treated with Valproic Acid] results in increased expression of MRRF mRNA; [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MRRF mRNAPMID:17183730 PMID:27188386
Go Back to source page   Continue to Ontology report