Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303089
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gsn
Name: gelsolin
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:13463756480464CTDValproic Acid results in increased expression of GSN mRNA

PMID:19101580, PMID:23179753, PMID:24383497, PMID:24935251, PMID:26272509, PMID:27188386
increases expressionISORGD:15506606480464CTDValproic Acid results in increased expression of GSN mRNA

PMID:20546886
multiple interactionsISORGD:13463756480464CTD[Hydralazine co-treated with Valproic Acid] results in increased expression of GSN mRNA, [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GSN mRNA

PMID:17183730, PMID:27188386
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.