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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737011
Species: Mus musculus
RGD Object: Gene
Symbol: Hand1
Name: heart and neural crest derivatives expressed 1
Acc ID: CHEBI:3962
Term: curcumin
Definition: A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa.
Chemical ID: MESH:D003474
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDCurcumin results in decreased expression of HAND1 mRNA

PMID:24857828
multiple interactionsEXP 6480464CTDCurcumin inhibits the reaction [Alcohols results in increased expression of HAND1 mRNA]

PMID:24857828
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.