GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccne1 | decreases expression | ISO | Ccne1 (Rattus norvegicus) | 6480464 | CTD | Curcumin results in decreased expression of CCNE1 mRNA | PMID:18299980 | Ccne1 | decreases expression | ISO | CCNE1 (Homo sapiens) | 6480464 | CTD | Curcumin results in decreased expression of CCNE1 protein | PMID:17148446 PMID:36640941 | Ccne1 | increases degradation | ISO | CCNE1 (Homo sapiens) | 6480464 | CTD | Curcumin results in increased degradation of CCNE1 protein | PMID:18156803 | Ccne1 | multiple interactions | ISO | CCNE1 (Homo sapiens) | 6480464 | CTD | Curcumin inhibits the reaction [4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine results in increased expression of CCNE1 protein]; Curcumin inhibits the reaction [Sirolimus results in increased expression of CCNE1 protein]; lactacystin inhibits the reaction [Curcumin results in increased degradation of CCNE1 protein] | PMID:18156803 PMID:36640941 | |
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