Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621647
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vip
Name: vasoactive intestinal peptide
Acc ID: CHEBI:3962
Term: curcumin
Definition: A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa.
Chemical ID: MESH:D003474
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDCurcumin inhibits the reaction [VIP protein results in increased expression of PTGS2 protein]

PMID:17434257
multiple interactionsISORGD:13489316480464CTDCurcumin inhibits the reaction [VIP protein results in increased activity of MMP2 protein], Curcumin inhibits the reaction [VIP protein results in increased activity of MMP9 protein], Curcumin inhibits the reaction [VIP protein results in increased expression of CCND1 protein]

PMID:19189304
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.