GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Vdr | multiple interactions | ISO | VDR (Homo sapiens) | 6480464 | CTD | [Curcumin binds to and results in increased activity of VDR protein] which results in increased expression of CDKN1A mRNA; [Curcumin binds to and results in increased activity of VDR protein] which results in increased expression of CYP24A1 mRNA; [Curcumin binds to and results in increased activity of VDR protein] which results in increased expression of CYP3A4 mRNA; [Curcumin binds to and results in increased activity of VDR protein] which results in increased expression of TRPV6 mRNA; Curcumin binds to and results in increased activity of VDR protein; Curcumin inhibits the reaction [1,25-dihydroxy-26,27-dimethylcholecalciferol binds to VDR protein]; Curcumin promotes the reaction [VDR protein binds to NCOA1 protein]; Curcumin promotes the reaction [VDR protein binds to RXRA protein] | PMID:20153625 | |
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