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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1604618
Species: Homo sapiens
RGD Object: Gene
Symbol: CYCS
Name: cytochrome c, somatic
Acc ID: CHEBI:3962
Term: curcumin
Definition: A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa.
Chemical ID: MESH:D003474
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYCSaffects localizationEXP 6480464CTDCurcumin affects the localization of CYCS proteinPMID:19235267
CYCSmultiple interactionsEXP 6480464CTD[Arsenic Trioxide co-treated with Curcumin] results in increased expression of CYCS protein; [Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] which results in increased expression of CYCS proteinPMID:27430728 PMID:33617879
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