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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1346818
Species: Homo sapiens
RGD Object: Gene
Symbol: IDO1
Name: indoleamine 2,3-dioxygenase 1
Acc ID: CHEBI:3962
Term: curcumin
Definition: A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa.
Chemical ID: MESH:D003474
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IDO1decreases expressionEXP 6480464CTDCurcumin results in decreased expression of IDO1 mRNAPMID:18348204
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