GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nfkbia | decreases phosphorylation | EXP | | 6480464 | CTD | Curcumin results in decreased phosphorylation of NFKBIA protein | PMID:17885582 | Nfkbia | multiple interactions | EXP | | 6480464 | CTD | Curcumin inhibits the reaction [Fluorouracil results in decreased expression of NFKBIA protein]; Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of NFKBIA protein] | PMID:27194111 PMID:34272803 | Nfkbia | decreases expression | ISO | NFKBIA (Homo sapiens) | 6480464 | CTD | Curcumin results in decreased expression of NFKBIA protein | PMID:16023083 | Nfkbia | decreases phosphorylation | ISO | NFKBIA (Homo sapiens) | 6480464 | CTD | Curcumin results in decreased phosphorylation of NFKBIA protein | PMID:16023083 PMID:17289836 | Nfkbia | increases expression | ISO | NFKBIA (Homo sapiens) | 6480464 | CTD | Curcumin results in increased expression of NFKBIA protein | PMID:12216086 PMID:17927689 | Nfkbia | multiple interactions | ISO | Nfkbia (Rattus norvegicus) | 6480464 | CTD | CD40 protein affects the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]]; Curcumin analog inhibits the reaction [Copper Sulfate results in increased expression of NFKBIA mRNA]; Curcumin inhibits the reaction [Copper Sulfate results in increased expression of NFKBIA mRNA]; Curcumin inhibits the reaction [Fructose results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased degradation of NFKBIA protein]; ICAM1 protein affects the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]] | PMID:15793857 PMID:16934299 PMID:26713546 PMID:30431687 PMID:35549587 | Nfkbia | multiple interactions | ISO | NFKBIA (Homo sapiens) | 6480464 | CTD | Curcumin inhibits the reaction [Acetylmuramyl-Alanyl-Isoglutamine results in increased phosphorylation of NFKBIA protein]; Curcumin inhibits the reaction [bisphenol A results in increased expression of NFKBIA protein modified form]; Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NFKBIA mRNA]; Curcumin inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [IL1B protein results in increased phosphorylation of NFKBIA protein]; Curcumin inhibits the reaction [NFKBIA protein results in increased degradation of RELA protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of NFKBIA mRNA]; Curcumin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of NFKBIA protein]; Curcumin inhibits the reaction [Paclitaxel results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [Sodium Fluoride results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]; NFKBIA protein affects the reaction [Curcumin results in decreased expression of CXCL1 mRNA]; NFKBIA protein affects the reaction [Curcumin results in decreased expression of CXCL2 mRNA]; NFKBIA protein inhibits the reaction [Curcumin results in decreased expression of CCN2 mRNA] | PMID:15489888 PMID:16219905 PMID:16243823 PMID:16819191 PMID:17291458 PMID:17666914 PMID:17927689 PMID:17965732 PMID:17999991 PMID:18413660 PMID:23452621 PMID:25540590 PMID:29793316 PMID:31521693 | | ||||||||||||||||||||||
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