GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | SLC31A1 | increases expression | EXP | | 6480464 | CTD | Trientine results in increased expression of SLC31A1 mRNA; Trientine results in increased expression of SLC31A1 protein | PMID:22914438 | SLC31A1 | multiple interactions | EXP | | 6480464 | CTD | [Trientine results in increased expression of SLC31A1 mRNA] which results in decreased susceptibility to oxaliplatin; [Trientine results in increased expression of SLC31A1 mRNA] which results in increased susceptibility to Carboplatin; [Trientine results in increased expression of SLC31A1 mRNA] which results in increased susceptibility to Cisplatin; Trientine promotes the reaction [SLC31A1 protein results in increased uptake of Platinum] | PMID:22491798 PMID:22914438 | SLC31A1 | increases expression | ISO | Slc31a1 (Rattus norvegicus) | 6480464 | CTD | Trientine results in increased expression of SLC31A1 mRNA | PMID:22362149 | | ||||||||||||||||||||||
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