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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11160
Species: Mus musculus
RGD Object: Gene
Symbol: Prnp
Name: prion protein
Acc ID: CHEBI:39501
Term: 2,2,2-tetramine
Definition: A polyazaalkane that is decane in which the carbon atoms at positions 1, 4, 7 and 10 are replaced by nitrogens.
Chemical ID: MESH:D014266
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prnpaffects response to substanceISOPrnp (Rattus norvegicus)6480464CTDPRNP protein affects the susceptibility to TrientinePMID:22362149
Prnpincreases expressionISOPrnp (Rattus norvegicus)6480464CTDTrientine results in increased expression of PRNP mRNA; Trientine results in increased expression of PRNP proteinPMID:22362149
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