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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735868
Species: Homo sapiens
RGD Object: Gene
Symbol: NQO1
Name: NAD(P)H quinone dehydrogenase 1
Acc ID: CHEBI:39483
Term: sodium dichromate
Definition: An inorganic sodium salt that has formula Cr2Na2O7.
Chemical ID: MESH:C016104
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDsodium bichromate results in increased expression of NQO1 protein

PMID:28624442
affects expressionISORGD:25036480464CTDsodium bichromate affects the expression of NQO1 mRNA

PMID:22110744
decreases expressionISORGD:104736480464CTDsodium bichromate results in decreased expression of NQO1 mRNA

PMID:22613061
increases expressionISORGD:25036480464CTDsodium bichromate results in increased expression of NQO1 mRNA

PMID:12325037, PMID:25993096
multiple interactionsISORGD:104736480464CTD[Benzo(a)pyrene co-treated with sodium bichromate] results in decreased expression of NQO1 mRNA, Benzo(a)pyrene promotes the reaction [sodium bichromate results in decreased expression of NQO1 mRNA]

PMID:22613061
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.