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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2595
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fbp1
Name: fructose-bisphosphatase 1
Acc ID: CHEBI:39483
Term: sodium dichromate
Definition: An inorganic sodium salt that has formula Cr2Na2O7.
Chemical ID: MESH:C016104
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fbp1affects response to substanceISOFBP1 (Homo sapiens)6480464CTDFBP1 protein affects the susceptibility to sodium bichromatePMID:28624442
Fbp1decreases expressionISOFBP1 (Homo sapiens)6480464CTDsodium bichromate results in decreased expression of FBP1 mRNA; sodium bichromate results in decreased expression of FBP1 proteinPMID:28624442
Fbp1multiple interactionsISOFBP1 (Homo sapiens)6480464CTDFBP1 protein inhibits the reaction [sodium bichromate results in decreased expression of JUN protein]; FBP1 protein inhibits the reaction [sodium bichromate results in increased expression of BCL2 protein]; FBP1 protein inhibits the reaction [sodium bichromate results in increased expression of BCL2L1 protein]; FBP1 protein inhibits the reaction [sodium bichromate results in increased expression of CDKN1A protein]; FBP1 protein inhibits the reaction [sodium bichromate results in increased expression of NOTCH1 protein]; FBP1 protein inhibits the reaction [sodium bichromate results in increased expression of SOD2 protein]; FBP1 protein promotes the reaction [sodium bichromate results in increased cleavage of PARP1 protein]; FBP1 protein promotes the reaction [sodium bichromate results in increased expression of CASP3 protein modified form]; FBP1 protein promotes the reaction [sodium bichromate results in increased expression of CASP9 protein modified form]PMID:28624442
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