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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1353911
Species: Homo sapiens
RGD Object: Gene
Symbol: OGG1
Name: 8-oxoguanine DNA glycosylase
Acc ID: CHEBI:39483
Term: sodium dichromate
Definition: An inorganic sodium salt that has formula Cr2Na2O7.
Chemical ID: MESH:C016104
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
OGG1decreases expressionEXP 6480464CTDsodium bichromate results in decreased expression of OGG1 mRNA; sodium bichromate results in decreased expression of OGG1 proteinPMID:11756223
OGG1increases response to substanceEXP 6480464CTDOGG1 protein polymorphism results in increased susceptibility to sodium bichromatePMID:15734978
OGG1increases expressionISOOgg1 (Rattus norvegicus)6480464CTDsodium bichromate results in increased expression of OGG1 mRNAPMID:22561333
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