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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733996
Species: Homo sapiens
RGD Object: Gene
Symbol: PSMA1
Name: proteasome 20S subunit alpha 1
Acc ID: CHEBI:39421
Term: perfluorooctane-1-sulfonic acid
Definition: A perfluoroalkanesulfonic acid that is octane-1-sulfonic acid in which all seventeen of the hydrogens that are attached to carbons hvae been replaced by fluorines.
Chemical ID: MESH:C076994
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PSMA1affects expressionISOPsma1 (Mus musculus)6480464CTDperfluorooctane sulfonic acid affects the expression of PSMA1 mRNAPMID:19429403
PSMA1increases expressionISOPsma1 (Mus musculus)6480464CTDperfluorooctane sulfonic acid results in increased expression of PSMA1 mRNAPMID:20936131
PSMA1multiple interactionsISOPsma1 (Mus musculus)6480464CTD[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PSMA1 mRNA; [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of PSMA1 mRNA; [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of PSMA1 mRNA; PPARA protein promotes the reaction [perfluorooctane sulfonic acid results in increased expression of PSMA1 mRNA]PMID:20936131 PMID:36331819
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