GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | MAPK8 | increases expression | EXP | | 6480464 | CTD | perfluorooctane sulfonic acid results in increased expression of MAPK8 mRNA | PMID:36988283 | MAPK8 | increases phosphorylation | EXP | | 6480464 | CTD | perfluorooctane sulfonic acid results in increased phosphorylation of MAPK8 protein | PMID:36988283 | MAPK8 | multiple interactions | EXP | | 6480464 | CTD | [perfluorooctane sulfonic acid results in increased phosphorylation of and results in increased activity of MAPK8 protein] which affects the localization of BAX protein; acetovanillone inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of MAPK8 mRNA]; acetovanillone inhibits the reaction [perfluorooctane sulfonic acid results in increased phosphorylation of MAPK8 protein]; Cannabidiol inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of MAPK8 mRNA]; Cannabidiol inhibits the reaction [perfluorooctane sulfonic acid results in increased phosphorylation of MAPK8 protein]; perfluorooctane sulfonic acid results in increased phosphorylation of and results in increased activity of MAPK8 protein | PMID:34006824 PMID:36988283 | MAPK8 | decreases phosphorylation | ISO | Mapk8 (Rattus norvegicus) | 6480464 | CTD | perfluorooctane sulfonic acid results in decreased phosphorylation of MAPK8 protein | PMID:28973641 | MAPK8 | increases expression | ISO | Mapk8 (Mus musculus) | 6480464 | CTD | perfluorooctane sulfonic acid results in increased expression of MAPK8 mRNA | PMID:36988283 | MAPK8 | increases phosphorylation | ISO | Mapk8 (Mus musculus) | 6480464 | CTD | perfluorooctane sulfonic acid results in increased phosphorylation of MAPK8 protein | PMID:36988283 | MAPK8 | multiple interactions | ISO | Mapk8 (Mus musculus) | 6480464 | CTD | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of MAPK8 mRNA; Cannabidiol inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of MAPK8 mRNA]; Cannabidiol inhibits the reaction [perfluorooctane sulfonic acid results in increased phosphorylation of MAPK8 protein] | PMID:36331819 PMID:36988283 | |
Go Back to source page | Continue to Ontology report |