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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620607
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cox5a
Name: cytochrome c oxidase subunit 5A
Acc ID: CHEBI:39421
Term: perfluorooctane-1-sulfonic acid
Definition: A perfluoroalkanesulfonic acid that is octane-1-sulfonic acid in which all seventeen of the hydrogens that are attached to carbons hvae been replaced by fluorines.
Chemical ID: MESH:C076994
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cox5adecreases expressionISOCox5a (Mus musculus)6480464CTDperfluorooctane sulfonic acid results in decreased expression of COX5A mRNAPMID:20936131
Cox5amultiple interactionsISOCox5a (Mus musculus)6480464CTDPPARA protein inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of COX5A mRNA]PMID:20936131
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