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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1553327
Species: Mus musculus
RGD Object: Gene
Symbol: Psmd8
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
Acc ID: CHEBI:39421
Term: perfluorooctane-1-sulfonic acid
Definition: A perfluoroalkanesulfonic acid that is octane-1-sulfonic acid in which all seventeen of the hydrogens that are attached to carbons hvae been replaced by fluorines.
Chemical ID: MESH:C076994
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Psmd8affects expressionEXP 6480464CTDperfluorooctane sulfonic acid affects the expression of PSMD8 mRNAPMID:19429403
Psmd8increases expressionEXP 6480464CTDperfluorooctane sulfonic acid results in increased expression of PSMD8 mRNAPMID:20936131
Psmd8multiple interactionsEXP 6480464CTD[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PSMD8 mRNA; [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of PSMD8 mRNA; PPARA protein promotes the reaction [perfluorooctane sulfonic acid results in increased expression of PSMD8 mRNA]PMID:20936131 PMID:36331819
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